Job Description

Materials Sciences is an integral part of the drug development process, connecting chemical synthesis with drug formulation to give a safe, effective drug product. Different crystal structures (polymorphs) of a compound, or salts of that compound have different physical properties which can impact solubility, stability, bioavailability, developability and formulation of the drug. It is therefore essential to select the right solid form. It is also important to understand how the selected solid form is impacted by formulation components and conditions.

Jazz Discovery and Medicinal Chemistry (D&MC) is looking for a motivated Materials Sciences summer student, within the Pre-Formulation & Biopharmaceutics team. The 6-week placement is designed to introduce a selected student to key Materials Sciences activities and responsibilities as part of the early drug development process, including crystallization process development, solid form selection and physical properties characterization. The placement will be suitable for a student who has an interest in pursuing a Pharmaceutical Sciences career and wishes to get an understanding of this area of science. The position will complement and significantly add to their university learning and provide a highly valuable industrial experience. It will also give insight into how the Jazz Pre-Formulation & Biopharmaceutics team contributes to the overall success of the company, whilst putting the patient at the forefront of what we do.

Job Responsibilities

Working very closely with the assigned supervisor on:

• Learning and understanding the importance and implementation of the laboratory risk assessment process, to underpin safe laboratory working.

• Completion of safety training before working in the lab, adhering to safety and housekeeping rules.

• Conducting laboratory operational tasks and experiments as instructed, in a timely manner, promptly reporting any unexpected results or events to the supervisor.

• Learning how to interpret their own experimental observations/results and manage their daily workload.

• Using specialist computers, software and equipment, following appropriate training.

• Learning and developing an understanding of Materials Sciences, physical properties characterization and process development as part of the early development Chemistry, Manufacturing and Controls (CMC) process.

• Effectively communicating and presenting their own work in team meetings, interacting with other team members.

• Recording experiments within the company’s electronic lab notebook in a timely manner, ensuring write-ups are complete and reviewed by the end of the placement.

• Completing any associated university assignments.